Using metals as healing stimuli has been practiced for thousands of years by healers and alchemists in their attempts to find a universal elixir. By combining the modern science of bioelectricity with the ancient wisdom of Chinese medicine theory of meridians and Qi (energy) flow, we may have solved this healing enigma. When electrodes are placed on specific acupuncture points of our electrolyte bodies, according to the protocols, they generate an ionic charge, resulting in a beneficial physiological response in injured and diseased cells and tissues. Bio-electrode Therapy offers a new bioelectronic approach that significantly reduces or eliminates the pain of opioid withdrawal and recovery as well as many types of complex pain, often the original cause of opioid dependence. The cost is minimal, and there are no side effects. Health care professional and, with supervision, even the patients themselves can learn to apply Bio-electrode Therapy protocols themselves.