Endogenous DC Electric Fields and Qi
- les moncrieff
- Oct 31
- 1 min read
Briefly, many human bodily functions (heart, brain, muscle movement, etc.) are dependent on electrical factors. In a recent PubMed Journal article, researchers. M.A. Messerli and D.M. Graham have written:
Endogenous DC electric fields (EFs) are important, fundamental components of development, regeneration, and wound healing. The fields are the result of polarized ion transport and current flow through electrically conductive pathways. Nullification of endogenous EFs with pharmacological agents or applied EFs of opposite polarity disturbs the aforementioned processes, while enhancement increases the rate of wound closure and the extent of regeneration. EFs are applied to humans in the clinic to provide an overwhelming signal for the enhancement of the healing of chronic wounds. Although clinical trials, spanning a course of decades, have shown that applied EFs enhance the healing of chronic wounds, the mechanisms by which cells sense and respond to these weak cues remain unknown. EFs are thought to influence many different processes in vivo.
However, under more rigorously controlled conditions in vitro, applied EFs induce cellular polarity and direct migration and outgrowth. Here, we review the generation of endogenous EFs, the results of their alteration, and the mechanisms by which cells may sense these weak fields. Understanding the mechanisms by which native and applied EFs direct development and repair will enable current and future therapeutic applications to be optimized.
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